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ANIMAL SCIENCES
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Larry Reynolds
Professor

Office: 175 Hultz Hall
Phone: (701) 231-7646
E-mail: larry.reynolds@ndsu.edu

Web-page: www.ndsu.nodak.edu/ndsu/lreynold

Research interests:

Normal growth, development and function of tissues, including the uterus and placenta, are dependent on an adequate blood supply. Fetal growth is highly correlated with the rate of blood flow to the uterus and placenta. Dr. Reynolds' primary research emphasizes the physiological mechanisms regulating uterine and placental vascular growth and function, using in vitro (including histological, cellular, and molecular) approaches. The goal is to minimize embryonic death and optimize fetal growth and development and thus postnatal survival and growth in livestock.

Training/Education:
Post-doctoral Nutrition - US MARC/USDA, Clay Center, Nebraska -1983-85
Ph.D., Reproductive Physiology, Arizona State University -1983
M.S., Reproductive Physiology, Arizona State University -1980
B.S., Zoology, Arizona State University -1977

Courses taught:
ANSC 263 - Introduction to Animal Biotechnology (Guest Lecture)
ANSC 357 - Animal Genetics (Guest Lecture)
ANSC 488 - Dairy Industry & Production Systems (Guest Lecture)
ANSC 728 - Advanced Reproductive Biology
ANSC 730 - Growth Biology

Recent publications:
1. Reynolds, L.P. and D.A. Redmer. 1995. Utero-placental vascular development and placental function. Review Article. J. Anim. Sci. 73:1839-1851.

2. Redmer, D.A., Y. Dai, J. Li, D.S. Charnock-Jones, S.K. Smith, L.P. Reynolds and R.M. Moor. 1996. Characterization and expression of vascular endothelial
growth factor (VEGF) in the ovine corpus luteum. J. Reprod. Fertil. 108:157-165.

3. Redmer, D.A and L.P. Reynolds. 1996. Angiogenesis in the ovary. Review Article. Rev. Reprod. 1:182-192.

4. Zheng, J., M.L. Johnson, D.A. Redmer and L.P. Reynolds. 1996. Estrogen and progesterone receptors, cell proliferation, and c-fos expression in the ovine uterus during early pregnancy. Endocrinology 137:340-348.

5. Grazul-Bilska, A.T., L.P. Reynolds and D.A. Redmer. 1997. Minireview. Gap Junctions in the Ovary. Review Article. Biol. Reprod. 52:947-957

6. Grazul-Bilska, A.T., D.A. Redmer and L.P. Reynolds. 1998. Cellular interactions within the corpus luteum. Review Article. Seminars in Reprod. Endocrinol. 15:383-393.

7. Reynolds, L.P. and D.A. Redmer. 1998. Expression of the angiogenic factors, basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF), in the ovary. Review Article. J. Anim. Sci. 76:1671-1681.

8. Reynolds, L.P., J.D. Kirsch, K.C. Kraft, D.L. Knutson, W.J. McClaflin and D.A. Redmer. 1998. Time-course of the uterine response to estradiol-17ß in ovariectomized ewes: Uterine growth and microvascular development. Biol. Reprod. 59:606-612.

9. Reynolds, L.P., J.D. Kirsch, K.C. Kraft and D.A. Redmer. 1998. Time-course of the uterine response to estradiol-17ß in ovariectomized ewes: Expression of angiogenic factors. Biol. Reprod. 59:613-620.

10. Zheng, J., D.A. Redmer, S.D. Killilea, and L.P. Reynolds. 1998. Characterization of heparin-binding endothelial mitogens produced by the ovine endometrium during early pregnancy. Biochem. Cell Biol. 76:89-96.

11. Reynolds, L.P., A.T. Grazul-Bilska and D.A. Redmer. 2000. Angiogenesis in the corpus luteum. Review Article. Endocrine 12:1-9. Redmer DA, Doraiswamy V, Bortnem BJ, Fisher K, Jablonka-Shariff A, Grazul-Bilska AT, and Reynolds LP. 2001. Evidence for a role of capillary pericytes in vascular growth of the developing ovine corpus luteum. Biol. Reprod. 65:879-889.



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