Chung Park
Professor
Office: 193 Hultz Hall
Phone: (701) 231-7670
E-mail: c.park@ndsu.edu
Research interests:
Nutritional regulation of animal growth, mammary development, lactation, and mammary tumorigenesis.
Training/Education:
Postdoc, Mammary Biology, Purdue University, Lafayette - 1977-78
Postdoc, Lactation Physiology, Virginia Polytechnic & State University, Blacksfurg, 1975-77
Ph.D., Nutritional Physiology, Virginia Polytechnic and State University, Blacksfurg, 1975
M.S., Ruminant Nutrition, University of Georgia, Athens,1972
B.S., Animal Science, Seoul National University, Korea, 1964
Appointments:
1988-present:Professor, Dept. of Animal Sciences, North Dakota State Univ., Fargo
1994-1994:Interim Chair, Dept. of Animal Sciences, North Dakota State Univ., Fargo
1985-1986:Visiting Professor, Dept, of Cell Biology, Lawrence Berkeley National Laboratory, University of California, Berkeley (Dr. Mina Bissell)
1986-1986: Visiting Professor, Dept. of Medicine/Oncology, Stanford University Medical School, Stanford (Dr. Frank Stockdale)
1982-1988:Associate Professor, Dept. of Animal Sciences, North Dakota State Univ., Fargo
1978-1982: Assistant Professor, Dept. of Animal Sciences, North Dakota State Univ., Fargo
Courses taught:
ANSC 488 (Undergraduate capstone course): 1994-present
ANSC 721 (Graduate course): 1979-present
Research Projects (Past 5 years):
Ongoing Research Support
USDA - National Research Initiative: Role of Compensatory Growth in Lactation
USDA-CSREES: Canola Oil Suppresses Human Breast Cancer Cell Growth
Department of Defense–Medical Research Program: In Utero Exposure to Dietary Methyl Nutrients and Breast Cancer Risk in Offspring
Completed Research Support
NIH-National Cancer Institute: Lipotrope Stimulates Breast Cancer Cell Death
USDA-CSREES: Nutraceuticals and Canola: Altering Conjugated Linoleic Acid in Milk
Representive's publications:
Book Chapters
Park, C.S. 2002. Heifer rearing for optimum lifetime production. In Recent Developments in Ruminant Nutrition 4. (P.C. Garnsworthy and J. Wiseman, eds.), Nottingham University Press, Nottingham, England. Pp 581-596.
Park, C.S., and G.L. Lindberg. 2004. The mammary gland and lactation. In Dukes’ Physiology of Domestic Animals 12th ed., (W.O. Reece, ed.), Cornell University Press, Ithaca, NY. Pp 720-741.
Refereed Journal Articles
Park, C.S., Y.J. Choi, W.L. Keller, and R.L. Harrold. 1988. Effects of compensatory growth on milk protein gene expression and mammary differentiation. FASEB J. 2:2619-2624.
Baik, M., C.B. Choi, W.L. Keller, and C.S. Park. 1992. Developmental stages and energy restriction affect cellular oncogene expression in tissues of female rats. J. Nutr. 122:1614-1620.
Choi, C.B., M.G. Baik, W.L. Keller, and C.S. Park. 1993. Lipotrope-modified diets enhance nitrosomethylurea-induced mammary carcinogenesis in female rats. Nutr. Cancer 20:215-221.
Kim, S.H., Y.S. Moon, W.L. Keller, and C.S. Park. 1998. Compensatory nutrition-directed mammary cell proliferation and lactation in rats. Br. J. Nutr. 79:177-183.
Wu, D., W.L. Keller, and C.S. Park. 1998. Lipotrope deficiency inhibits cell growth and induces programmed cell death in human breast cancer cell line MCF-7. Nutr. Cancer 32:13-19.
Moon, Y.S., and C. S. Park. 1999. Nutritionally directed compensatory growth enhances mammary development and lactation potential in rats. J. Nutr. 129:1156-1160.
Joo, N.E., and C.S. Park. 2003. Inhibition of excitotoxicity in cultured rat cortical neurons by a mixture of conjugated linoleic acid isomers. Pharmacol. Res. 47:305-310.
Kim, H.H., and C.S. Park. 2004. A compensatory nutrition regimen during gestation stimulates mammary development and lactation potential in rats. J Nutr. 134:756-761.
Park, C.S. 2005. Role of compensatory mammary growth in epigenetic control of gene expression. FASEB J. 19:1586-1591.
Park C.S., Cho K.S., Bae D.R., Joo N.E., Kim H.H., Mabasa L., Fowler A.W. 2008. Methyl-Donor Nutrients Inhibit Breast Cancer Cell Growth. In Vitro Cell. Dev. Biol. Anim. 44:268-272.
Synergistic Activities (Year 2009):
PI’s laboratory has mentored 22 graduate students (9 Ph.D. and 13 M.S.). Currently two doctorate students are working in the PI’s lab.
He has been appointed by The Animal Production and Health Section of the Joint Food and Agriculture Organization and International Atomic Energy Agency Division of the UN to coordinate a research project to study effective nutrition regimens for sustainable food production systems for both developing and industrialized countries. Based on the compensatory growth model studied in his laboratory, this 5-year multi-national project will focus on developing practical nutrition programs and strategies that enhance lactation potential and muscle tissue development of livestock.